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Suppression of endoplasmic reticulum stress improves endothelium-dependent contractile responses in aorta of the spontaneously hypertensive rat

A contributing factor to increased peripheral resistance seen during hypertension is an increased production of endothelium-derived contractile factors (EDCFs). The main EDCFs are vasoconstrictor prostanoids, metabolites of arachidonic acid (AA) produced by Ca(2+)-dependent cytosolic phospholipase A...

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Detalhes bibliográficos
Main Authors: Spitler, Kathryn M., Matsumoto, Takayuki, Webb, R. Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742878/
https://ncbi.nlm.nih.gov/pubmed/23709602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00952.2012
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