Deletion of cationic amino acid transporter 2 exacerbates dextran sulfate sodium colitis and leads to an IL-17-predominant T cell response

l-Arginine (l-Arg) is a semiessential amino acid that has altered availability in human ulcerative colitis (UC), a form of inflammatory bowel disease, and is beneficial in murine colitis induced by dextran sulfate sodium (DSS), a model with similarity to UC. We assessed the role of cationic amino ac...

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Hlavní autoři: Singh, Kshipra, Coburn, Lori A., Barry, Daniel P., Asim, Mohammad, Scull, Brooks P., Allaman, Margaret M., Lewis, Nuruddeen D., Washington, M. Kay, Rosen, Michael J., Williams, Christopher S., Chaturvedi, Rupesh, Wilson, Keith T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Inflammation/Immunity/Mediators
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742860/
https://ncbi.nlm.nih.gov/pubmed/23703655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00091.2013
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