Thrombospondin-1 regulates adiposity and metabolic dysfunction in diet-induced obesity enhancing adipose inflammation and stimulating adipocyte proliferation

As a typical matricellular protein, thrombospondin (TSP)-1, binds to the structural matrix and regulates cellular behavior by modulating growth factor and cytokine signaling. Obesity and diabetes are associated with marked upregulation of TSP-1 in adipose tissue. We hypothesized that endogenous TSP-...

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Detaylı Bibliyografya
Asıl Yazarlar: Kong, Ping, Gonzalez-Quesada, Carlos, Li, Na, Cavalera, Michele, Lee, Dong-Wook, Frangogiannis, Nikolaos G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742854/
https://ncbi.nlm.nih.gov/pubmed/23757408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00006.2013
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