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Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

Autophagy is an essential cellular mechanism for cell homeostasis and survival by which damaged cellular proteins are sequestered in autophagosomal vesicles and cleared through lysosomal machinery. The autophagy pathway also plays an important role in immunity and inflammation via pathogen clearance...

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Autores principales: Itakura, Asako, McCarty, Owen J. T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742850/
https://ncbi.nlm.nih.gov/pubmed/23720022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00108.2013
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