An In Silico Analysis of Troponin I Mutations in Hypertrophic Cardiomyopathy of Indian Origin

Hypertrophic Cardiomyopathy (HCM) is an autosomal dominant disorder of the myocardium which is hypertrophied resulting in arrhythmias and heart failure leading to sudden cardiac death (SCD). Several sarcomeric proteins and modifier genes have been implicated in this disease. Troponin I, being a part...

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Detalhes bibliográficos
Main Authors: Ramachandran, Gayatri, Kumar, Manoj, Selvi Rani, Deepa, Annanthapur, Venkateshwari, Calambur, Narasimhan, Nallari, Pratibha, Kaur, Punit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742764/
https://ncbi.nlm.nih.gov/pubmed/23967088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070704
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