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TLR4 is a novel determinant of the response to paclitaxel in breast cancer

Overexpression of Toll-like Receptor-4 (TLR4) in human tumors often correlates with chemoresistance and metastasis. We found that TLR4 is overexpressed in the majority of clinical breast cancer (BC) samples and in 68% of the examined BC lines. TLR4 is activated by lipopolysaccharide (LPS) and other...

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Detalhes bibliográficos
Main Authors: Rajput, Sandeep, Volk-Draper, Lisa D., Ran, Sophia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742631/
https://ncbi.nlm.nih.gov/pubmed/23720768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1019
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