2-Methoxyestradiol Induces Mitotic Arrest, Apoptosis, and Synergistic Cytotoxicity with Arsenic Trioxide in Human Urothelial Carcinoma Cells

2-Methoxyestradiol (2-ME), an endogenous derivative of 17β-estradiol, has been reported to elicit antiproliferative responses in various tumors. In this study, we investigated the effects of 2-ME on cell viability, proliferation, cell cycle, and apoptosis in human urothelial carcinoma (UC) cell line...

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Autors principals: Kuo, Kuan-Lin, Lin, Wei-Chou, Ho, I-Lin, Chang, Hong-Chiang, Lee, Ping-Yi, Chung, Yuan-Ting, Hsieh, Ju-Ton, Pu, Yeong-Shiau, Shi, Chung-Sheng, Huang, Kuo-How
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742604/
https://ncbi.nlm.nih.gov/pubmed/23967052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068703
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