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Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled

Replication forks formed at bacterial origins often encounter template roadblocks in the form of DNA adducts and frozen protein–DNA complexes, leading to replication-fork stalling and inactivation. Subsequent correction of the corrupting template lesion and origin-independent assembly of a new repli...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: McGlynn, Peter, Lloyd, Robert G., Marians, Kenneth J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Colloquium Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459958/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121007798
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