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Camkii-Mediated Phosphorylation Regulates Distributions of Syngap-α1 and –α2 at the Postsynaptic Density

SynGAP, a protein abundant at the postsynaptic density (PSD) of glutamatergic neurons, is known to modulate synaptic strength by regulating the incorporation of AMPA receptors at the synapse. Two isoforms of SynGAP, α1 and α2, which differ in their C-termini, have opposing effects on synaptic streng...

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Detalhes bibliográficos
Main Authors: Yang, Yijung, Tao-Cheng, Jung-Hwa, Bayer, K. Ulrich, Reese, Thomas S., Dosemeci, Ayse
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742523/
https://ncbi.nlm.nih.gov/pubmed/23967245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071795
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