Protective Effects of Metallothionein on Isoniazid and Rifampicin-Induced Hepatotoxicity in Mice

Isoniazid (INH) and Rifampicin (RFP) are widely used in the world for the treatment of tuberculosis, but the hepatotoxicity is a major concern during clinical therapy. Previous studies showed that these drugs induced oxidative stress in liver, and several antioxidants abated this effect. Metallothio...

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Detalhes bibliográficos
Main Authors: Lian, Yong, Zhao, Jing, Xu, Peiyu, Wang, Yimei, Zhao, Jun, Jia, Li, Fu, Ze, Jing, Li, Liu, Gang, Peng, Shuangqing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742471/
https://ncbi.nlm.nih.gov/pubmed/23967274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072058
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