Reduced Juvenile Long-Term Depression in Tuberous Sclerosis Complex Is Mitigated in Adults by Compensatory Recruitment of mGluR5 and Erk Signaling

Tuberous sclerosis complex (TSC) is a multisystem genetic disease that manifests with mental retardation, tumor formation, autism, and epilepsy. Heightened signaling through the mammalian target of rapamycin (mTOR) pathway is involved in TSC pathology, however it remains unclear how other signaling...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Potter, Wyatt B., Basu, Trina, O'Riordan, Kenneth J., Kirchner, Allison, Rutecki, Paul, Burger, Corinna, Roopra, Avtar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742461/
https://ncbi.nlm.nih.gov/pubmed/23966835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001627
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