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MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4
MDM2 Binding Protein (MTBP) has been implicated in cancer progression. Here we demonstrate one mechanism by which MTBP inhibits cancer metastasis. Overexpression of MTBP in human osteosarcoma cell lines lacking wild-type p53 did not alter primary tumor growth in mice but significantly inhibited meta...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742333/ https://ncbi.nlm.nih.gov/pubmed/22370640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.69 |
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