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Mitochondrial targeted antioxidant peptide ameliorates hypertensive cardiomyopathy

OBJECTIVES: We investigated the effect of reducing mitochondrial oxidative stress by the mitochondrial-targeted antioxidant peptide SS-31 in hypertensive cardiomyopathy. BACKGROUND: Oxidative stress has been implicated in hypertensive cardiovascular diseases. Mitochondria and NADPH oxidase have been...

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Hlavní autoři: Dai, Dao-Fu, Chen, Tony, Szeto, Hazel, Nieves-Cintrón, Madeline, Kutyavin, Vassily, Santana, Luis F., Rabinovitch, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742010/
https://ncbi.nlm.nih.gov/pubmed/21620606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.12.044
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