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Functional role of ambient GABA in refining neuronal circuits early in postnatal development

Early in development, γ-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the mature brain, depolarizes and excites targeted neurons by an outwardly directed flux of chloride, resulting from the peculiar balance between the cation-chloride importer NKCC1 and the extruder KCC2. The...

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Detalhes bibliográficos
Main Authors: Cellot, Giada, Cherubini, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741556/
https://ncbi.nlm.nih.gov/pubmed/23964205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2013.00136
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