MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation

In patients with Duchenne muscular dystrophy (DMD), the absence of a functional dystrophin protein results in sarcolemmal instability, abnormal calcium signaling, cardiomyopathy, and skeletal muscle degeneration. Using the dystrophin-deficient sapje zebrafish model, we have identified microRNAs (miR...

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Detalhes bibliográficos
Main Authors: Alexander, M S, Kawahara, G, Motohashi, N, Casar, J C, Eisenberg, I, Myers, J A, Gasperini, M J, Estrella, E A, Kho, A T, Mitsuhashi, S, Shapiro, F, Kang, P B, Kunkel, L M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741500/
https://ncbi.nlm.nih.gov/pubmed/23764775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.62
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