Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells

Notch1 has been reported to be highly expressed in triple-negative and other subtypes of breast cancer. Mutant p53 (R280K) is overexpressed in MDA-MB-231 triple-negative human breast cancer cells. The present study aimed to determine whether the mutant p53 can be a potent transcriptional activator o...

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Detalhes bibliográficos
Main Authors: Bae, Yun-Hee, Ryu, Jong Hyo, Park, Hyun-Joo, Kim, Kwang Rok, Wee, Hee-Jun, Lee, Ok-Hee, Jang, Hye-Ock, Bae, Moon-Kyoung, Kim, Kyu-Won, Bae, Soo-Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741485/
https://ncbi.nlm.nih.gov/pubmed/23946688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2013.17.4.291
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