Lentiviral Vector-Mediated Gradients of GDNF in the Injured Peripheral Nerve: Effects on Nerve Coil Formation, Schwann Cell Maturation and Myelination

Although the peripheral nerve is capable of regeneration, only a small minority of patients regain normal function after surgical reconstruction of a major peripheral nerve lesion, resulting in a severe and lasting negative impact on the quality of life. Glial cell-line derived neurotrophic factor (...

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Autores principales: Eggers, Ruben, de Winter, Fred, Hoyng, Stefan A., Roet, Kasper C. D., Ehlert, Erich M., Malessy, Martijn J. A., Verhaagen, Joost, Tannemaat, Martijn R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741360/
https://ncbi.nlm.nih.gov/pubmed/23951085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071076
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