Kinetics of Reversible Reductive Carbonylation of Heme in Human Cystathionine β-synthase

Cystathionine β-synthase (CBS) catalyzes the condensation of homocysteine with serine or cysteine to form cystathionine and water or hydrogen sulfide (H(2)S), respectively. In addition to pyridoxal phosphate, human CBS has a heme cofactor with cysteine and histidine as ligands. While Fe(III)-CBS is...

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Bibliographic Details
Main Authors: Carballal, Sebastián, Cuevasanta, Ernesto, Marmisolle, Inés, Kabil, Omer, Gherasim, Carmen, Ballou, David P., Banerjee, Ruma, Alvarez, Beatriz
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741107/
https://ncbi.nlm.nih.gov/pubmed/23790103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4004556
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