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Notch signaling modulates sleep homeostasis and learning after sleep deprivation in Drosophila

The role of the trans-membrane receptor Notch in the adult brain is poorly understood. Here, we provide evidence that bunched, a negative regulator of Notch is involved in sleep homeostasis. Genetic evidence indicates that interfering with bunched activity in the mushroom bodies (MBs) abolishes slee...

詳細記述

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書誌詳細
主要な著者: Seugnet, Laurent, Suzuki, Yasuko, Merlin, Gabriel, Gottschalk, Laura, Duntley, Stephen P., Shaw, Paul J
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741064/
https://ncbi.nlm.nih.gov/pubmed/21549599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.04.001
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