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Notch signaling modulates sleep homeostasis and learning after sleep deprivation in Drosophila

The role of the trans-membrane receptor Notch in the adult brain is poorly understood. Here, we provide evidence that bunched, a negative regulator of Notch is involved in sleep homeostasis. Genetic evidence indicates that interfering with bunched activity in the mushroom bodies (MBs) abolishes slee...

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Detalhes bibliográficos
Main Authors: Seugnet, Laurent, Suzuki, Yasuko, Merlin, Gabriel, Gottschalk, Laura, Duntley, Stephen P., Shaw, Paul J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741064/
https://ncbi.nlm.nih.gov/pubmed/21549599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.04.001
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