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Tissue-specific HIV-1 infection: why it matters

The human immunodeficiency virus displays a narrow tropism for CD4(+) mononuclear cells, and activated CD4(+) T lymphocytes are the main target. When these cells are depleted by viral replication, bystander apoptosis and increased cell turnover mediated by immune activation, there is a progressive i...

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Detalles Bibliográficos
Main Authors: Karris, Maile AY, Smith, Davey M
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741055/
https://ncbi.nlm.nih.gov/pubmed/23946764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.11.48
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