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In vivo synaptic recovery following optogenetic hyperstimulation
Local recycling of synaptic vesicles (SVs) allows neurons to sustain transmitter release. Extreme activity (e.g., during seizure) may exhaust synaptic transmission and, in vitro, induces bulk endocytosis to recover SV membrane and proteins; how this occurs in animals is unknown. Following optogeneti...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740886/ https://ncbi.nlm.nih.gov/pubmed/23878262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305679110 |
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