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In vivo synaptic recovery following optogenetic hyperstimulation

Local recycling of synaptic vesicles (SVs) allows neurons to sustain transmitter release. Extreme activity (e.g., during seizure) may exhaust synaptic transmission and, in vitro, induces bulk endocytosis to recover SV membrane and proteins; how this occurs in animals is unknown. Following optogeneti...

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Detalhes bibliográficos
Main Authors: Kittelmann, Maike, Liewald, Jana F., Hegermann, Jan, Schultheis, Christian, Brauner, Martin, Steuer Costa, Wagner, Wabnig, Sebastian, Eimer, Stefan, Gottschalk, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740886/
https://ncbi.nlm.nih.gov/pubmed/23878262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305679110
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