Ca(2+) release-activated Ca(2+) channel blockade as a potential tool in antipancreatitis therapy

Alcohol-related acute pancreatitis can be mediated by a combination of alcohol and fatty acids (fatty acid ethyl esters) and is initiated by a sustained elevation of the Ca(2+) concentration inside pancreatic acinar cells ([Ca(2+)](i)), due to excessive release of Ca(2+) stored inside the cells foll...

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Hauptverfasser: Gerasimenko, Julia V., Gryshchenko, Oleksiy, Ferdek, Pawel E., Stapleton, Eloise, Hébert, Tania O. G., Bychkova, Solomiia, Peng, Shuang, Begg, Malcolm, Gerasimenko, Oleg V., Petersen, Ole H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740877/
https://ncbi.nlm.nih.gov/pubmed/23878235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300910110
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