Phase I Study Combining Treatment with Temsirolimus and Sunitinib Malate in Patients with Advanced Renal Cell Carcinoma

PURPOSE: Concurrent inhibition of multiple oncogenic signaling pathways might improve the efficacy of anticancer agents and abrogate resistance mechanisms. This phase I study evaluated temsirolimus in combination with sunitinib in patients with advanced RCC. PATIENTS AND METHODS: Eligibility include...

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Hlavní autoři: Patel, Premal H., Senico, Peggy L., Curiel, Rafael E., Motzer, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740755/
https://ncbi.nlm.nih.gov/pubmed/19213664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3816/CGC.2009.n.004
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