Platelet-activating factor-induced NF-κ B activation and IL-8 production in intestinal epithelial cells are Bcl10 dependent

BACKGROUND: Platelet-activating factor (PAF), a potent pro-inflammatory phospholipid mediator, has been implicated in inducing intestinal inflammation in diseases such as inflammatory bowel disease (IBD) and necrotizing enterocolitis (NEC). However, its mechanisms of inducing inflammatory responses...

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Autores principales: Borthakur, Alip, Bhattacharyya, Sumit, Alrefai, Waddah A., Tobacman, Joanne K., Ramaswamy, Krishnamurthy, Dudeja, Pradeep K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740729/
https://ncbi.nlm.nih.gov/pubmed/19714753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21092
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