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CD3 Monoclonal Antibodies: A First Step Towards Operational Immune Tolerance in the Clinic
Type 1 diabetes (T1D) is a prototypic organ-specific autoimmune disease resulting from the selective destruction of insulin-secreting β-cells within the pancreatic islets of Langerhans. It is caused by an immune-mediated inflammation, involving autoreactive CD4(+) and CD8(+) T lymphocytes that infil...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SBDR - Society for Biomedical Diabetes Research
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740704/ https://ncbi.nlm.nih.gov/pubmed/23804274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.372 |
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