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Protein Tyrosine Phosphatases and Type 1 Diabetes: Genetic and Functional Implications of PTPN2 and PTPN22

Protein tyrosine phosphatases (PTPs) play a central role in modulating the transduction of cellular signals, including the cells of the immune system. Several PTPs, PTPN22, PTPN2, and UBASH3A, have been associated with risk of type 1 diabetes (T1D) by genome wide association studies. Based on the cu...

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Detalhes bibliográficos
Main Authors: Cerosaletti, Karen, Buckner, Jane H.
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740690/
https://ncbi.nlm.nih.gov/pubmed/23804260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.188
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