The Pharmacokinetics of Acyl, Desacyl and Total Ghrelin in Healthy Human Subjects

BACKGROUND: Ghrelin stimulates growth hormone (GH) secretion and regulates energy and glucose metabolism. The two circulating isoforms, acyl (AG) and desacyl (DAG) ghrelin, have distinct metabolic effects and are under active investigation for their therapeutic potentials. However, there is only lim...

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Main Authors: Tong, Jenny, Dave, Nimita, Mugundu, Ganesh M., Davis, Harold W, Gaylinn, Bruce D., Thorner, Michael O., Tschöp, Matthias H, D’Alessio, David, Desai, Pankaj B.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740531/
https://ncbi.nlm.nih.gov/pubmed/23482590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-13-0072
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