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N-acetylgalactosamine-functionalized dendrimers as hepatic cancer cell-targeted carriers

There is an urgent need for novel polymeric carriers that can selectively deliver a large dose of chemotherapeutic agents into hepatic cancer cells to achieve high therapeutic activity with minimal systemic side effects. PAMAM dendrimers are characterized by a unique branching architecture and a lar...

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Detalhes bibliográficos
Main Authors: Medina, Scott H., Tekumalla, Venkatesh, Chevliakov, Maxim V., Shewach, Donna S., Ensminger, William D., El-Sayed, Mohamed E.H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740328/
https://ncbi.nlm.nih.gov/pubmed/21429574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.11.068
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