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Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines pharmacokinetic-pharmacodynamic modeling, repeated small doses of a challeng...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
PeerJ Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740141/ https://ncbi.nlm.nih.gov/pubmed/23940831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.117 |
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