Integrated stress response of Escherichia coli to methylglyoxal: transcriptional readthrough from the nemRA operon enhances protection through increased expression of glyoxalase I

Methylglyoxal (MG) elicits activation of K(+) efflux systems to protect cells against the toxicity of the electrophile. ChIP-chip targeting RNA polymerase, supported by a range of other biochemical measurements and mutant creation, was used to identify genes transcribed in response to MG and which c...

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Main Authors: Ozyamak, Ertan, Almeida, Camila, de Moura, Alessandro P S, Miller, Samantha, Booth, Ian R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739934/
https://ncbi.nlm.nih.gov/pubmed/23646895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12234
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