A Randomized, Phase 3 Trial of Naltrexone SR/Bupropion SR on Weight and Obesity-related Risk Factors (COR-II)

OBJECTIVE: To examine the effects of naltrexone/bupropion (NB) combination therapy on weight and weight-related risk factors in overweight and obese participants. DESIGN AND METHODS: CONTRAVE Obesity Research-II (COR-II) was a double-blind, placebo-controlled study of 1,496 obese (BMI 30-45 kg/m(2))...

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Главные авторы: Apovian, Caroline M, Aronne, Louis, Rubino, Domenica, Still, Christopher, Wyatt, Holly, Burns, Colleen, Kim, Dennis, Dunayevich, Eduardo
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2013
Предметы:
Clinical Trials: Behavior, Pharmacotherapy, Devices, Surgery
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739931/
https://ncbi.nlm.nih.gov/pubmed/23408728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20309
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