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MicroRNA-185 and 342 Inhibit Tumorigenicity and Induce Apoptosis through Blockade of the SREBP Metabolic Pathway in Prostate Cancer Cells

MicroRNA (miRNA or miR) inhibition of oncogenic related pathways has been shown to be a promising therapeutic approach for cancer. Aberrant lipid and cholesterol metabolism is involved in prostate cancer development and progression to end-stage disease. We recently demonstrated that a key transcript...

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Detalhes bibliográficos
Main Authors: Li, Xiangyan, Chen, Yi-Ting, Josson, Sajni, Mukhopadhyay, Nishit K., Kim, Jayoung, Freeman, Michael R., Huang, Wen-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739799/
https://ncbi.nlm.nih.gov/pubmed/23951060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070987
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