Thioredoxin-1 Attenuates Early Graft Loss after Intraportal Islet Transplantation in Mice

AIMS: Recent studies suggest that decreasing oxidative stress is crucial to achieve successful islet transplantation. Thioredoxin-1 (TRX), which is a multifunctional redox-active protein, has been reported to suppress oxidative stress. Furthermore, it also has anti-inflammatory and anti-apoptotic ef...

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Main Authors: Asami, Kengo, Inagaki, Akiko, Imura, Takehiro, Sekiguchi, Satoshi, Fujimori, Keisei, Masutani, Hiroshi, Yodoi, Junji, Satomi, Susumu, Ohuchi, Noriaki, Goto, Masafumi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739792/
https://ncbi.nlm.nih.gov/pubmed/23950917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070259
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