Loss of ACE2 Exacerbates Murine Renal Ischemia-Reperfusion Injury

Ischemia-reperfusion (I/R) is a model of acute kidney injury (AKI) that is characterized by vasoconstriction, oxidative stress, apoptosis and inflammation. Previous studies have shown that activation of the renin-angiotensin system (RAS) may contribute to these processes. Angiotensin converting enzy...

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Autors principals: Fang, Fei, Liu, George Chu, Zhou, Xiaohua, Yang, Stuart, Reich, Heather Naomi, Williams, Vanessa, Hu, Amanda, Pan, Janice, Konvalinka, Ana, Oudit, Gavin Yadram, Scholey, James William, John, Rohan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739768/
https://ncbi.nlm.nih.gov/pubmed/23951161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071433
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