Protein Tyrosine Phosphatase 1B Deficiency Ameliorates Murine Experimental Colitis via the Expansion of Myeloid-Derived Suppressor Cells

Protein tyrosine phosphatase 1B (PTP1B) is a key molecule in modulating low-degree inflammatory conditions such as diabetes. The role of PTP1B in other chronic inflammations, however, remains unknown. Here, we report that PTP1B deficiency ameliorates Dextran Sulfate Sodium (DSS)-induced murine exper...

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Main Authors: Zhang, Jing, Wang, Bing, Zhang, Wen, Wei, Yao, Bian, Zhen, Zhang, Chen-Yu, Li, Limin, Zen, Ke
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739765/
https://ncbi.nlm.nih.gov/pubmed/23951017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070828
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