Hypomethylation of Noncoding DNA Regions and Overexpression of the Long Noncoding RNA, AFAP1-AS1, in Barrett’s Esophagus and Esophageal Adenocarcinoma

BACKGROUND & AIMS: Alterations in methylation of protein-coding genes are associated with Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC). Dys-regulation of noncoding RNAs occurs during carcinogen-esis but has never been studied in BE or EAC. We applied high-resolution methylome ana...

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Main Authors: Wu, Wenjing, Bhagat, Tushar D., Yang, Xue, Song, Jee Hoon, Cheng, Yulan, Agarwal, Rachana, Abraham, John M., Ibrahim, Sariat, Bartenstein, Matthias, Hussain, Zulfiqar, Suzuki, Masako, Yu, Yiting, Chen, Wei, Eng, Charis, Greally, John, Verma, Amit, Meltzer, Stephen J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739703/
https://ncbi.nlm.nih.gov/pubmed/23333711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.019
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