Preparation and immunogenicity of tag-free recombinant human eppin

Human epididymal protease inhibitor (eppin) may be effective as a male contraceptive vaccine. In a number of studies, eppin with an engineered His(6)-tag has been produced using prokaryotic expression systems. For production of pharmaceutical-grade proteins for human use, however, the His(6)-tag mus...

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Autores principales: Zhang, Jie, Ding, Xin-Liang, Bian, Zeng-Hui, Xia, Yan-Kai, Wang, Shou-Lin, Song, Ling, Wang, Xin-Ru
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739548/
https://ncbi.nlm.nih.gov/pubmed/21892195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.89
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