Microenvironment-Dependent Phenotypic Changes in a SCID Mouse Model for Malignant Mesothelioma

Background and Aims: Malignant mesothelioma is an aggressive, therapy-resistant tumor. Mesothelioma cells may assume an epithelioid or a sarcomatoid phenotype, and presence of sarcomatoid cells predicts poor prognosis. In this study, we investigated differentiation of mesothelioma cells in a xenogra...

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Detalhes bibliográficos
Main Authors: Darai-Ramqvist, Eva, Nilsonne, Gustav, Flores-Staino, Carmen, Hjerpe, Anders, Dobra, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739415/
https://ncbi.nlm.nih.gov/pubmed/23951555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00203
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