AF-2364 is a prospective spermicide candidate

Inhibition of sperm motility has recently become a promising target for male contraceptive development. AF-2364, an analogue of Lonidamine (LND), had a contraceptive effect when orally administered to adult Sprague–Dawley rats. LND can also target mitochondria to inhibit oxygen consumption and block...

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Bibliografiske detaljer
Main Authors: Wang, Hui, Chen, Xiang-Xiang, Wang, Li-Rong, Mao, Yun-Dong, Zhou, Zuo-Min, Sha, Jia-Hao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739263/
https://ncbi.nlm.nih.gov/pubmed/20418891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.11
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