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Transgelin induces apoptosis of human prostate LNCaP cells through its interaction with p53
The androgen receptor (AR) and its coregulators have important roles in the carcinogenesis of prostate cancer. p53 is an important tumour suppressor gene, and the absence of a fundamental p53 response may predispose to cancer. Transgelin, known as an ARA54-associated AR inhibitor, can suppress AR fu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739090/ https://ncbi.nlm.nih.gov/pubmed/20098441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2009.76 |
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