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Genetic engineering of T-cell receptors: TCR takes to titin
In this issue of Blood, Linette et al report a cautionary tale—a lethal off-target toxicity following T-cell receptor (TCR) optimization to enhance affinity against a tumor-associated antigen, MAGE-A3.(1)
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739034/ https://ncbi.nlm.nih.gov/pubmed/23929832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-06-509604 |
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