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Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients

INTRODUCTION: Amplification of the ESR1 gene, coding for estrogen receptor alpha, was shown to predict responsiveness to tamoxifen, however its prognostic impact in breast cancer patients has not been thoroughly investigated. Other factors that could contribute to responsiveness to tamoxifen treatme...

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Detalhes bibliográficos
Main Authors: Markiewicz, Aleksandra, Wełnicka-Jaśkiewicz, Marzena, Skokowski, Jarosław, Jaśkiewicz, Janusz, Szade, Jolanta, Jassem, Jacek, Żaczek, Anna J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738574/
https://ncbi.nlm.nih.gov/pubmed/23951298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072219
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