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Specific Inhibition of Tumor Cells by Oncogenic EGFR Specific Silencing by RNA interference

Anticancer agents that have minimal effects on normal cells and tissues are ideal cancer drugs. Here, we show specific inhibition of human cancer cells carrying oncogenic mutations in the epidermal growth factor receptor (EGFR) gene by means of oncogenic allele-specific RNA interference (RNAi), both...

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Autori principali: Takahashi, Masaki, Chiyo, Tomoko, Okada, Takashi, Hohjoh, Hirohiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738543/
https://ncbi.nlm.nih.gov/pubmed/23951344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073214
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