OXIDATIVE INHIBITION OF RECEPTOR TYPE PROTEIN TYROSINE PHOSPHATASE KAPPA BY ULTRAVIOLET IRRADIATION ACTIVATES EGFR IN HUMAN KERATINOCYTES

Ultraviolet (UV) irradiation rapidly increases tyrosine phosphorylation (i.e. activates) of epidermal growth factor receptors (EGFR) in human skin. EGFR-dependent signaling pathways drive increased expression of matrix-metalloproteinases, whose actions fragment collagen and elastin fibers, the prima...

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Autors principals: Xu, Yiru, Shao, Yuan, Voorhees, John J., Fisher, Gary J
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738260/
https://ncbi.nlm.nih.gov/pubmed/16849327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602355200
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