OXIDATIVE INHIBITION OF RECEPTOR TYPE PROTEIN TYROSINE PHOSPHATASE KAPPA BY ULTRAVIOLET IRRADIATION ACTIVATES EGFR IN HUMAN KERATINOCYTES

Ultraviolet (UV) irradiation rapidly increases tyrosine phosphorylation (i.e. activates) of epidermal growth factor receptors (EGFR) in human skin. EGFR-dependent signaling pathways drive increased expression of matrix-metalloproteinases, whose actions fragment collagen and elastin fibers, the prima...

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Main Authors: Xu, Yiru, Shao, Yuan, Voorhees, John J., Fisher, Gary J
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738260/
https://ncbi.nlm.nih.gov/pubmed/16849327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602355200
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