The Phospholipase C Inhibitor U73122 Attenuates trans-10, cis-12 Conjugated Linoleic Acid-Mediated Inflammatory Signaling and Insulin Resistance in Human Adipocytes(1)(2)

We have demonstrated that trans-10, cis-12 conjugated linoleic acid (18:2t10,c12)-mediated delipidation of human adipocytes was dependent on increased intracellular calcium and activation of inflammatory signaling in human primary adipocytes. These data are consistent with the actions of diacylglyce...

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Detalles Bibliográficos
Main Authors: Shen, Wan, Martinez, Kristina, Chuang, Chia Chi, McIntosh, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Nutrition 2013
Assuntos:
Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738231/
https://ncbi.nlm.nih.gov/pubmed/23468551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.112.173161
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