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STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) activation is frequently found in human lung cancer and is associated with increased metastasis and reduced survival. How STAT3 enhances invasiveness is unclear. METHODS: The expression of microRNAs and target genes was measured...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, H-Y, Chiang, C-H, Hung, W-C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738132/
https://ncbi.nlm.nih.gov/pubmed/23820254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.349
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