A comparison of the detection of BRCA mutation carriers through the provision of Jewish population-based genetic testing compared with clinic-based genetic testing

BACKGROUND: Guidelines for genetic testing for BRCA1 or BRCA2 stipulate that a personal or family history of cancer is necessary to be eligible for testing. Approximately 2% of Ashkenazi Jewish women carry a mutation, but to date population-based testing has not been advocated. Little is known about...

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Detalhes bibliográficos
Main Authors: Metcalfe, K A, Poll, A, Royer, R, Nanda, S, Llacuachaqui, M, Sun, P, Narod, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738109/
https://ncbi.nlm.nih.gov/pubmed/23778531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.309
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