The Effects of Eszopiclone on Sleep Spindles and Memory Consolidation in Schizophrenia: A Randomized Placebo-Controlled Trial

STUDY OBJECTIVES: In schizophrenia there is a dramatic reduction of sleep spindles that predicts deficient sleep-dependent memory consolidation. Eszopiclone (Lunesta), a non-benzodiazepine hypnotic, acts on γ-aminobutyric acid (GABA) neurons in the thalamic reticular nucleus where spindles are gener...

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Detalhes bibliográficos
Main Authors: Wamsley, Erin J., Shinn, Ann K., Tucker, Matthew A., Ono, Kim E., McKinley, Sophia K., Ely, Alice V., Goff, Donald C., Stickgold, Robert, Manoach, Dara S.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2013
Assuntos:
Effects of Eszopiclone on Sleep and Memory in Schizophrenia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738047/
https://ncbi.nlm.nih.gov/pubmed/23997371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.2968
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