Splicing-coupled 3′ end formation requires a terminal splice acceptor site, but not intron excision

Splicing of human pre-mRNA is reciprocally coupled to 3′ end formation by terminal exon definition, which occurs co-transcriptionally. It is required for the final maturation of most human pre-mRNAs and is therefore important to understand. We have used several strategies to block splicing at specif...

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Bibliographic Details
Main Authors: Davidson, Lee, West, Steven
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737548/
https://ncbi.nlm.nih.gov/pubmed/23716637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt446
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