FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD

FUS is genetically and pathologically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). To clarify the RNA metabolism cascade regulated by FUS in ALS/FTLD, we compared the FUS-regulated transcriptome profiles in different lineages of primary cells from the c...

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Main Authors: Fujioka, Yusuke, Ishigaki, Shinsuke, Masuda, Akio, Iguchi, Yohei, Udagawa, Tsuyoshi, Watanabe, Hirohisa, Katsuno, Masahisa, Ohno, Kinji, Sobue, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737506/
https://ncbi.nlm.nih.gov/pubmed/23925123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02388
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